1 Content of labeling must be identical to the enclosed labeling (Prescribing Information), with the addition of any labeling changes in pending “Changes Being Jul 20, 2023 · In patients receiving hydroxyurea for sickle cell anemia, withhold therapy when neutrophil count is <2000/mm 3, the platelet count is <80,000/mm 3, the hemoglobin concentration is <4
2
2 Laboratory Test Interference Dec 19, 2023 · HYDREA ® (hydroxyurea capsules, USP) is supplied as 500 mg capsules in HDPE bottles with a plastic safety screw cap
Inactive ingredients:
Molecular formula: CH 4 N 2 O 2 CAS number: 127-07-1 Medically reviewed by Drugs
This medicine is used to treat certain types of leukemias and head and neck cancer
Revised: 11/2019
It is also
C
The chemical name of voxelotor is: 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
Hydroxyurea is an antineoplastic agent used alone or in combination with other chemotherapeutic drugs or radiation in the treatment of resistant leukemias and carcinomas of the head and neck
Low blood cell counts
Hydroxyurea is indicated to reduce the frequency of painful crises and to reduce the need for blood transfusions in adult and pediatric patients, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises
2) DOSAGE AND ADMINISTRATION Doses should be individualized based on safety and efficacy
The capsules are imprinted on both sections with “HYDREA” and “830” in black ink ( NDC 0003-0830-50)
It is also used to control the painful crises of sickle cell anemia
COLOR: green
It may also be given together with radiation treatment for head and neck cancer (advanced squamous cell cancer)
Inactive ingredients: anhydrous citric acid, benzyl alcohol, black iron oxide, butylparaben, carboxymethylcellulose sodium, D & C red no
Prophylactic administration of folic acid is recommended [ see Warnings and Precautions (5
• QTc interval greater than 480 msec to 500 msec • Monitor and supplement electrolyte levels as clinically indicated [see Warnings and Precautions (5
Common adverse reactions include myelosuppression
Prophylactic administration of folic acid is recommended [see Warnings and Precautions (5
Hydroxyurea oral capsule is available as the brand-name drugs Hydrea and Droxia The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose
Monitor blood counts at least once a week during Hydroxyurea capsules therapy
A skin lump or growth