• The main features of LTG-induced DIHS do not differ in sex group
One important type of SCAR is Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) – a complex, multisystem, and possibly life-threatening drug response
Lamotrigine-induced DRESS
In conclusion, we have presented a case of a fatal acute necrotizing eosinophilic myocarditis caused by lamotrigine, which occurred during steroid taper
If you’re concerned about DRESS while taking Lamictal, we recommend that you talk with your medical professional
DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) In some cases, it is possible that the rash is simply a coincidence caused by something
In very rare cases
Each of these conditions manifests with a severe (some say "angry") rash which typically develops after two to eight weeks of drug use
Patients with DRESS syndrome typically present with rash, swelling, fever, and systemic manifestations
Immediate-release Lamictal can be used in children as young as 2 years old for seizure treatment as an add-on treatment to other seizure medication
Cyclophosphamide
In the first case, 8 purpura developed after 23 weeks of lamotrigine use and was located on the buttocks, knees, and ankles
Lamotrigine is widely used to prevent bipolar depression
Lamotrigine-induced DRESS was diagnosed with typical history and clinical and laboratory findings
Its use, however, has been limited by the risk of potentially life-threatening dermatological reactions, such as a drug reaction with eosinophilia and systemic symptoms (DRESS)
A 32-year-old female presented with diarrhea, two weeks after the initiation of lamotrigine
7 Lamotrigine-induced DRESS has been reported and is a well-known example of the relationship between dose, titration rate and rash
The manufacturer states that nearly all cases appear in the first two to eight weeks of therapy
Read the latest news and reviews about the drug as well as potential side effects and popular alternatives
Abdelnabi M, Elmassry M, Sekhon J, Benjanuwattra J